The San Francisco 49ers have been practicing in temperatures exceeding 90 degrees this week. Sunday's game against the ...

The San Francisco 49ers dropped to 2-3 on the season after a 24-23 Week 5 loss to the Arizona Cardinals at Levi's Stadium in ...

San Francisco 49ers head coach Kyle Shanahan and several others spoke with reporters after Sunday's 24-23 Week 5 loss against ...

Defensive end Nick Bosa said he has not lost confidence that the 49ers are capable of great things. But it was another great ...

The 49ers are expecting to be without their kicker for some time. Head coach Kyle Shanahan said after Sunday's loss to the ...

After a series of sluggish performances since becoming one of the NFL's highest-paid wide receivers, Brandon Aiyuk played like a man intent on silencing ...

NFL Nation reporters react to all the action, answering the biggest questions coming out of each game. Here's what we learned ...

The Madden Curse has once again cast its shadow, this time over San Francisco 49ers superstar Christian McCaffrey (CMC).

The San Francisco 49ers will be without second-year kicker Jake Moody for an extended period. Following Sunday's narrow 24-23 ...

The San Francisco 49ers face the Arizona Cardinals in a divisional matchup at Levi's Stadium, marking the 66th meeting in a ...

The San Francisco 49ers face the Arizona Cardinals in a divisional matchup at Levi's Stadium, marking the 66th meeting in a ...

Once again, the 49ers let a seemingly comfortable lead against an NFC West opponent wilt away. The Arizona Cardinals came back ...